Sexton, Patrick M. : rechercher sur Z-Library

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1

G Protein–Coupled Receptors Targeting Insulin Resistance, Obesity, and Type 2 Diabetes Mellitus

Riddy, Darren M., Delerive, Philippe, Summers, Roger J., Sexton, Patrick M., Langmead, Christopher J., Barker, Eric L.

Journal:

Pharmacological Reviews

Année:

2018

Langue:

english

Fichier:

PDF, 956 KB

english, 2018

2

Self-Hypnosis Training and Captivity Survival

Wood, Dennis Patrick, Sexton, John L.

Journal:

American Journal of Clinical Hypnosis

Année:

1997

Langue:

english

Fichier:

PDF, 706 KB

english, 1997

3

Mechanisms of signalling and biased agonism in G protein-coupled receptors

Wootten, Denise, Christopoulos, Arthur, Marti-Solano, Maria, Babu, M. Madan, Sexton, Patrick M.

Journal:

Nature Reviews Molecular Cell Biology

Année:

2018

Langue:

english

Fichier:

PDF, 6.08 MB

english, 2018

4

Allosteric Modulation of G Protein–Coupled Receptors

May, Lauren T., Leach, Katie, Sexton, Patrick M., Christopoulos, Arthur

Journal:

Annual Review of Pharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 643 KB

english, 2007

5

The Best of Both Worlds? Bitopic Orthosteric/Allosteric Ligands of G Protein–Coupled Receptors

Valant, Celine, Robert Lane, J., Sexton, Patrick M., Christopoulos, Arthur

Journal:

Annual Review of Pharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2012

6

Unsupervised anomaly detection in peripheral venous pressure signals with hidden Markov models

Hayat, Md Abul, Wu, Jingxian, Bonasso, Patrick C., Sexton, Kevin W., Jensen, Hanna K., Dassinger, Melvin S., Jensen, Morten O.

Journal:

Biomedical Signal Processing and Control

Année:

2020

Fichier:

PDF, 847 KB

2020

7

Hot embossing of micrographic elements in polypropylene

Patrick W. Leech, Robert A. Lee, Brett A. Sexton, Fiona Smith

Journal:

Microelectronic Engineering

Année:

2007

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2007

8

Nursing handovers: do we really need them?

Amanda Sexton, Connie Chan, Malcolm Elliott, John Stuart, Rohan Jayasuriya, Patrick Crookes

Journal:

Journal of Nursing Management

Année:

2004

Langue:

english

Fichier:

PDF, 77 KB

english, 2004

9

Evolution and Ecology of Species Range Limits

Sexton, Jason P., McIntyre, Patrick J., Angert, Amy L., Rice, Kevin J.

Journal:

Annual Review of Ecology Evolution and Systematics

Année:

2009

Langue:

english

Fichier:

PDF, 292 KB

english, 2009

10

Allosteric modulation of G protein-coupled receptors: A pharmacological perspective

Peter Keov, Patrick M. Sexton, Arthur Christopoulos

Journal:

Neuropharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 1.00 MB

english, 2011

11

Structure–function analysis of amino acid 74 of human RAMP1 and RAMP3 and its role in peptide interactions with adrenomedullin and calcitonin gene-related peptide receptors

Tao Qi, Kien Ly, David R. Poyner, George Christopoulos, Patrick M. Sexton, Debbie L. Hay

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 298 KB

english, 2011

12

Allosteric GPCR modulators: taking advantage of permissive receptor pharmacology

Katie Leach, Patrick M. Sexton, Arthur Christopoulos

Journal:

Trends in Pharmacological Sciences

Année:

2007

Langue:

english

Fichier:

PDF, 660 KB

english, 2007

13

Emerging paradigms in GPCR allostery: implications for drug discovery

Wootten, Denise, Christopoulos, Arthur, Sexton, Patrick M.

Journal:

Nature Reviews Drug Discovery

Année:

2013

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2013

14

Towards tissue-specific pharmacology: insights from the calcium-sensing receptor as a paradigm for GPCR (patho)physiological bias

Leach, Katie, Conigrave, Arthur D., Sexton, Patrick M., Christopoulos, Arthur

Journal:

Trends in Pharmacological Sciences

Année:

2015

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2015

15

Reliability Analysis of the 3-min All-Out Exercise Test for Cycle Ergometry

JOHNSON, TYLER M., SEXTON, PATRICK J., PLACEK, ASHLEY M., MURRAY, STEVEN R., PETTITT, ROBERT W.

Journal:

Medicine & Science in Sports & Exercise

Année:

2011

Langue:

english

Fichier:

PDF, 5.15 MB

english, 2011

16

Evolution and Ecology of Species Range Limits

Jason P. Sexton, Patrick J. McIntyre, Amy L. Angert and Kevin J. Rice

Journal:

Annual Review of Ecology Evolution and Systematics

Année:

2009

Fichier:

PDF, 3.77 MB

2009

17

Evolution and Ecology of Species Range Limits

Jason P. Sexton, Patrick J. McIntyre, Amy L. Angert and Kevin J. Rice

Journal:

Annual Review of Ecology Evolution and Systematics

Année:

2009

Langue:

english

Fichier:

PDF, 3.77 MB

english, 2009

18

Do the Noncaffeine Ingredients of Energy Drinks Affect Metabolic Responses to Heavy Exercise?

Pettitt, Robert W., Niemeyer, JoLynne D., Sexton, Patrick J., Lipetzky, Amanda, Murray, Steven R.

Journal:

The Journal of Strength and Conditioning Research

Année:

2013

Langue:

english

Fichier:

PDF, 166 KB

english, 2013

19

Single-Leg Balance Training: An Intervention Tool in the Reduction of Injuries

Sexton, Patrick, Palmer, Thomas G.

Journal:

Athletic Therapy Today

Année:

2007

Langue:

english

Fichier:

PDF, 156 KB

english, 2007

20

Unconventional Baseball Pitching Styles, Part 1: Biomechanics and Pathology

Mokha, Monique, Truedson, Thomas N., Sexton, Patrick J., Pettitt, Robert W.

Journal:

International Journal of Athletic Therapy and Training

Année:

2012

Langue:

english

Fichier:

PDF, 2.17 MB

english, 2012

21

Cenozoic North Atlantic deep circulation history recorded in contourite drifts, offshore Newfoundland, Canada

Boyle, Patrick R., Romans, Brian W., Tucholke, Brian E., Norris, Richard D., Swift, Stephen A., Sexton, Philip F.

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 10.72 MB

english, 2017

22

Structure of the Adenosine A1 Receptor Reveals the Basis for Subtype Selectivity

Glukhova, Alisa, Thal, David M., Nguyen, Anh T., Vecchio, Elizabeth A., Jörg, Manuela, Scammells, Peter J., May, Lauren T., Sexton, Patrick M., Christopoulos, Arthur

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 7.46 MB

english, 2017

23

Ion Channels in Genetic Epilepsy: From Genes and Mechanisms to Disease-Targeted Therapies

Oyrer, Julia, Maljevic, Snezana, Scheffer, Ingrid E., Berkovic, Samuel F., Petrou, Steven, Reid, Christopher A., Sexton, Patrick M.

Journal:

Pharmacological Reviews

Année:

2018

Langue:

english

Fichier:

PDF, 928 KB

english, 2018

24

Moderate Exercise Does Not Acutely Attenuate Cardiometabolic Function Associated with “Sitting Disease”

Younger, Amanda, Pettitt, Robert, Sexton, Patrick, Maass, William, Kernozek, Thomas W., Pettitt, Cherie

Journal:

Medicine & Science in Sports & Exercise

Année:

2015

Langue:

english

Fichier:

PDF, 492 KB

english, 2015

25

To Bind or Not to Bind: Unravelling GPCR Polypharmacology

Sexton, Patrick M., Christopoulos, Arthur

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 473 KB

english, 2018

26

Muscarinic M5 receptors modulate ethanol seeking in rats

Berizzi, Alice E., Perry, Christina J., Shackleford, David M., Lindsley, Craig W., Jones, Carrie K., Chen, Nicola A., Sexton, Patrick M., Christopoulos, Arthur, Langmead, Christopher J., Lawrence, And

Journal:

Neuropsychopharmacology

Année:

2018

Langue:

english

Fichier:

PDF, 1.31 MB

english, 2018

27

Extracellular loops 2 and 3 of the calcitonin receptor selectively modify agonist binding and efficacy

Dal Maso, Emma, Zhu, Yue, Pham, Vi, Reynolds, Christopher A., Deganutti, Giuseppe, Hick, Caroline A., Yang, Dehua, Christopoulos, Arthur, Hay, Debbie L., Wang, Ming-Wei, Sexton, Patrick M., Furness, S

Journal:

Biochemical Pharmacology

Année:

2018

Langue:

english

Fichier:

PDF, 5.59 MB

english, 2018

28

Structural insights into G-protein-coupled receptor allostery

Thal, David M., Glukhova, Alisa, Sexton, Patrick M., Christopoulos, Arthur

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 3.25 MB

english, 2018

29

Prospective, Double Blind Randomized Controlled Trial on the Use of Immediate Post-Operative Electrical Muscle Stimulation to Preserve Muscle Function and Volume Following Achilles Tendon Surgery

Hyer, Christopher, Berlet, Gregory, Wilgus, James, Collins, Christy, Houser, Joshua, Crill, Matthew, Sexton, Carrie, Stansbury, Emily, Bull, Patrick, Philbin, Terrence

Journal:

Foot & Ankle Orthopaedics

Année:

2017

Langue:

english

Fichier:

PDF, 202 KB

english, 2017

30

Bladder decompensation and reduction in nerve density in a rat model of chronic bladder outlet obstruction is attenuated with the NLRP3 inhibitor glyburide

Hughes, Francis Monty, Sexton, Stephanie J, Ledig, Patrick D, Yun, Chloe E, Jin, Huixia, Purves, J. Todd

Journal:

American journal of physiology. Renal physiology

Année:

2018

Langue:

english

Fichier:

PDF, 1.78 MB

english, 2018

31

MP09-16 PHARMACOLOGICAL INHIBITION OF THE NLRP3 INFLAMMASOME PREVENTS BLADDER DECOMPENSATION IN A RAT MODEL OF CHRONIC BLADDER OUTLET OBSTRUCTION

Hughes, Francis, Sexton, Stephanie, Leidig, Patrick, Jin, Huixia, Purves, J.

Journal:

The Journal of Urology

Année:

2018

Langue:

english

Fichier:

PDF, 165 KB

english, 2018

32

Light-activated chimeric GPCRs: limitations and opportunities

Tichy, Alexandra-Madelaine, Gerrard, Elliot J, Sexton, Patrick M, Janovjak, Harald

Journal:

Current Opinion in Structural Biology

Année:

2019

Langue:

english

Fichier:

PDF, 1.44 MB

english, 2019

33

Bone marrow transplantation and RNAseq analysis of Gpr21−/− monocytes reveals reduced migratory function and downregulation of inflammatory genes

Riddy, Darren M., Kammoun, Helene, Bosnyak-Gladovic, Sanja, Ziemann, Mark, Summers, Roger J., Sexton, Patrick M., Murphy, Andrew J., Langmead, Chris J.

Journal:

Obesity Research & Clinical Practice

Année:

2019

Langue:

english

Fichier:

PDF, 359 KB

english, 2019

34

Targeting Antibiotic Resistance: From Diagnostics to Novel Antibiotics

Li, Jian, Sexton, Patrick M.

Journal:

ACS Pharmacology & Translational Science

Année:

2020

Fichier:

PDF, 365 KB

2020

35

Evaluation of biased agonism mediated by dual agonists of the GLP-1 and glucagon receptors

Darbalaei, Sanaz, Yuliantie, Elita, Dai, Antao, Chang, Rulue, Zhao, Peishen, Yang, Dehua, Wang, Ming-Wei, Sexton, Patrick M., Wootten, Denise

Journal:

Biochemical Pharmacology

Année:

2020

Fichier:

PDF, 1.53 MB

2020

36

The effects of exposure to microgravity and reconditioning of the lumbar multifidus and anterolateral abdominal muscles; implications for people with LBP

Hides, Julie A., Lambrecht, Gunda, Sexton, Christopher T., Pruett, Casey, Petersen, Nora, Jaekel, Patrick, Rosenberger, AndrÃ©, Weerts, Guillaume

Journal:

The Spine Journal

Année:

2020

Fichier:

PDF, 2.99 MB

2020

37

In vitro autoradiographic localization of calcitonin binding sites in human medulla oblongata

Dr. Patrick M. Sexton, George Paxinos, Xu-Feng Huang, Frederick A. O. Mendelsohn

Journal:

The Journal of Comparative Neurology

Année:

1994

Langue:

english

Fichier:

PDF, 1.25 MB

english, 1994

38

Lipopolysaccharide supports survival and fusion of preosteoclasts independent of TNF-α, IL-1, and RANKL

Koji Suda, Je-Tae Woo, Masamichi Takami, Patrick M. Sexton, Kazuo Nagai

Journal:

Journal of Cellular Physiology

Année:

2002

Langue:

english

Fichier:

PDF, 290 KB

english, 2002

39

The CDF online system

D.R. Quarrie, M.D. Anderson, C.T. Day, G. Goeransson, J. Patrick, M. Schmitz, E. Sexton, B. Troemel

Journal:

Computer Physics Communications

Année:

1989

Langue:

english

Fichier:

PDF, 602 KB

english, 1989

40

Fabrication of hologram coins using electron beam lithography

Patrick W. Leech, Brett A. Sexton, Russell J. Marnock, Fiona Smith

Journal:

Microelectronic Engineering

Année:

2004

Langue:

english

Fichier:

PDF, 405 KB

english, 2004

41

3- and 6-Substituted 2-amino-4,5,6,7-tetrahydrothieno[2,3-c]pyridines as A1 adenosine receptor allosteric modulators and antagonists

Luigi Aurelio, Celine Valant, Heidi Figler, Bernard L. Flynn, Joel Linden, Patrick M. Sexton, Arthur Christopoulos, Peter J. Scammells

Journal:

Bioorganic & Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 470 KB

english, 2009

42

Benzodiazepine ligands can act as allosteric modulators of the Type 1 cholecystokinin receptor

Fan Gao, Patrick M. Sexton, Arthur Christopoulos, Laurence J. Miller

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2008

Langue:

english

Fichier:

PDF, 455 KB

english, 2008

43

The synthesis and biological evaluation of 2-amino-4,5,6,7,8,9-hexahydrocycloocta[b]thiophenes as allosteric modulators of the A1 adenosine receptor

Luigi Aurelio, Arthur Christopoulos, Bernard L. Flynn, Peter J. Scammells, Patrick M. Sexton, Celine Valant

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2011

Langue:

english

Fichier:

PDF, 452 KB

english, 2011

44

Photoaffinity scanning in the mapping of the peptide receptor interface of class II G protein—coupled receptors

Vi Pham, Patrick M. Sexton

Journal:

Journal of Peptide Science

Année:

2004

Langue:

english

Fichier:

PDF, 298 KB

english, 2004

45

Pattern of Intra-Family Hetero-Oligomerization Involving the G-Protein-Coupled Secretin Receptor

Kaleeckal G. Harikumar, Maria M. Morfis, Patrick M. Sexton, Laurence J. Miller

Journal:

Journal of Molecular Neuroscience

Année:

2008

Langue:

english

Fichier:

PDF, 260 KB

english, 2008

46

Scanning probe microscope analysis of microstructures in optically variable devices

Patrick W Leech, Brett A Sexton, Russell J Marnock

Journal:

Microelectronic Engineering

Année:

2002

Langue:

english

Fichier:

PDF, 932 KB

english, 2002

47

G-Protein-coupled receptor–protein interactions: Basis for new concepts on receptor structure and function

Nanda Tilakaratne, Patrick M Sexton

Journal:

Clinical and Experimental Pharmacology and Physiology

Année:

2005

Langue:

english

Fichier:

PDF, 78 KB

english, 2005

48

Characterization of serotonin 5-HT2C receptor signaling to extracellular signal-regulated kinases 1 and 2

Tim D. Werry, Karen J. Gregory, Patrick M. Sexton, Arthur Christopoulos

Journal:

Journal of Neurochemistry

Année:

2005

Langue:

english

Fichier:

PDF, 801 KB

english, 2005

49

Addition of a Carboxy-Terminal Green Fluorescent Protein Does Not Alter the Binding and Signaling Properties of Relaxin Family Peptide Receptor 3

Emma T. Van Der Westhuizen, John D. Wade, Patrick M. Sexton, Roger J. Summers

Journal:

Annals of the New York Academy of Sciences

Année:

2009

Langue:

english

Fichier:

PDF, 121 KB

english, 2009

50

Localization and characterization of renal calcitonin receptors by in vitro autoradiography

Sexton, Patrick M, Adam, William R, Moseley, Jane M, Martin, T John, Mendelsohn, Frederick A O

Journal:

Kidney International

Année:

1987

Langue:

english

Fichier:

PDF, 808 KB

english, 1987